Thomas W. Jeffries

Picture of Thomas W. Jeffries

Professor of Bacteriology, Emeritus

1550 Linden Drive

Phone: (608) 698-4470


Overview · Publications


Ph.D. 1975 Rutgers University
Postdoctoral Research: Columbia University

Areas of Study

Bioconversion of renewable resources
metabolic engineering of pentose fermenting yeasts

Research Overview

Our research interests are in the areas of microbial physiology, metabolic regulation and metabolic engineering as they apply to the utilization of lignocellulosic materials. This involves genetic engineering of novel yeasts, strain screening, scale-up, microbial biochemistry, and molecular genetics. Areas of emphasis are the fermentation of xylose by yeasts and metabolic pathway engineering. Research activities include metabolic engineering in the xylose-fermenting yeast, Pichia stipitis; optimization of metabolic pathways in Saccharomyces cerevisiae; determination of rate-limiting steps in yeast fermentation and growth; and alteration of intermediary metabolism to regulate energetics.